![]() Monit may also be used for purposes not listed in this medication guide. Monit will not treat an angina attack that has already begun. Monit is used to prevent angina attacks (chest pain). Monit dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump. Monit is in a group of drugs called nitrates. Single doses less than 20 mg have not been adequately studied, while single doses greater than 20 mg have demonstrated no greater efficacy than doses of 20 mg. In clinical trials, Monit tablets have been administered in a variety of regimens. The duration (if any) of antianginal activity beyond 12 hours has not been studied large controlled studies with other nitrates suggest that no dosing regimen should be expected to provide more than about 12 hours of continuous antianginal efficacy per day. This regimen has been shown to have antianginal efficacy beginning 1 hour after the first dose and lasting at least 5 hours after the second dose. The dosing regimen for Monit tablets provides a daily nitrate-free interval to avoid the development of this tolerance.Īs also noted under CLINICAL PHARMACOLOGY, well-controlled studies have shown that tolerance to Monit tablets is avoided when using the twice-daily regimen in which the two doses are given 7 hours apart. ![]() As noted above (CLINICAL PHARMACOLOGY), multiple studies of organic nitrates have shown that maintenance of continuous 24-hour plasma levels results in refractory tolerance. Dosage adjustments are not necessary for elderly patients or patients with altered renal or hepatic function. For most patients, this can be accomplished by taking the first dose on awakening and the second dose 7 hours later. The recommended regimen of Monit tablets is 20 mg (one tablet) twice daily, with the two doses given 7 hours apart. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician. Now fever, headache and body pains are the indications of paracetamol. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient.
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